Official Title
Comparative Study of Sedative Requirement Using Sevoflurane With Anaconda Device Versus Conventional Sedation in Patients With COVID-19
Brief Summary

At the beginning of 2020, a global alert emerged which saturated intensive care units dueto COVID-19 worldwide. This caused a need for mechanical ventilation due to atypicalpneumonias that had a rapid evolution and respiratory failure; therefore the consumptionof sedative agents in the intensive care units escalated. Suboptimal sedation in theintensive care unit, increases the adverse effects, costs, and morbidity. For the timebeing, they focus on the use of intravenous agents such as propofol or dexmedetomidine,which are associated with tolerance, withdrawal, delirium, and hemodynamic effects.Consequently, the need arises to maximize availability and effectiveness, which is whythe intervention of the ANACONDA conservation device is carried out, which works with aheat and humidity exchange filter capable of administering isoflurane or sevoflurane withan efficiency of 90%.

Detailed Description

Analyze the difference in intravenous sedation requirements in patients with COVID-19.
Patients who were assisted by a mechanical ventilator with sevoflurane versus
conventional sedation.

Completed
COVID-19
Respiratory Failure

Device: Sevoflurane with AnaConDa

Sevoflurane administered with AnaConDa device

Eligibility Criteria

Inclusion Criteria:

- Adult patients with confirmed COVI-19 infection and assited with mechanical
ventilation who entered critical care department.

Exclusion Criteria:

- Tranfers to a different hospital.

- Death within the first 24 hours of hospital stay.

Eligibility Gender
All
Eligibility Age
Minimum: 27 Years ~ Maximum: 85 Years
Countries
Mexico
Locations

Hospital H+ Queretaro
Querétaro City 3991164, Querétaro 3520914, Mexico

Manuel Lomeli, MD, Study Chair
Hospital H+ Queretaro

Universidad Nacional Autonoma de Mexico
NCT Number
Keywords
sedatives
Acute Kidney Injury
SARS-CoV-2
Mechanical Ventilation
MeSH Terms
COVID-19
Respiratory Insufficiency
Acute Kidney Injury