At the beginning of 2020, a global alert emerged which saturated intensive care units dueto COVID-19 worldwide. This caused a need for mechanical ventilation due to atypicalpneumonias that had a rapid evolution and respiratory failure; therefore the consumptionof sedative agents in the intensive care units escalated. Suboptimal sedation in theintensive care unit, increases the adverse effects, costs, and morbidity. For the timebeing, they focus on the use of intravenous agents such as propofol or dexmedetomidine,which are associated with tolerance, withdrawal, delirium, and hemodynamic effects.Consequently, the need arises to maximize availability and effectiveness, which is whythe intervention of the ANACONDA conservation device is carried out, which works with aheat and humidity exchange filter capable of administering isoflurane or sevoflurane withan efficiency of 90%.
Analyze the difference in intravenous sedation requirements in patients with COVID-19.
Patients who were assisted by a mechanical ventilator with sevoflurane versus
conventional sedation.
Device: Sevoflurane with AnaConDa
Sevoflurane administered with AnaConDa device
Inclusion Criteria:
  -  Adult patients with confirmed COVI-19 infection and assited with mechanical
     ventilation who entered critical care department.
Exclusion Criteria:
- Tranfers to a different hospital.
- Death within the first 24 hours of hospital stay.
Hospital H+ Queretaro
Querétaro City	3991164, Querétaro	3520914, Mexico
Manuel Lomeli, MD, Study Chair
 Hospital H+ Queretaro