This is a comparative prospective diagnostic accuracy study reported according to theSTARD guidelines. Citizens at an outpatient COVID19 test facility at Testcenter DanmarkValby will be invited to participate in the study on a volunteer basis. The enrolledparticipants will have the planned oropharyngeal swab performed in the test center andsent for a SARS-CoV-2 RT-PCR test at TestCenter Danmark, Statens Serum Institut,Copenhagen, Denmark as usual. Besides the planned oropharyngeal swab performed in thetest center, the participants will have additional specimens collected in form of saliva,nasopharyngeal-, nasal-, and oropharyngeal swabs. These will all be used for thedetection of nucleic acids from the four most common strains of influenza (B Yamagata, BVictoria, A H1N1 and A H3N2), SARS-CoV-2 and RSV A/B. Further we will measure immunemediating cytokines, chemokines, and interleukins in the different specimens. Theseanalyses will be performed at Technical University of Denmark (DTU).
Not Provided
Diagnostic Test: (NPS right - Nasal swab left - OPS)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (NPS left - Nasal swab right - OPS)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (Nasal swab right - NPS left - OPS)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (Nasal swab left - NPS right - OPS)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (NPS right - OPS - Nasal swab left)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (NPS left - OPS - Nasal swab right)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (Nasal swab right - OPS - NPS left)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (Nasal swab left - OPS - NPS right)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (OPS - NPS right - Nasal swab left)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (OPS - NPS left - Nasal swab right)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (OPS - Nasal swab left - NPS right)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
Diagnostic Test: (OPS - Nasal swab right - NPS left)
Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order
The inclusion criterion:
A. 18 years or more of age requiring a test for COVID-19.
The exclusion criteria are :
A. Neck breathers (tracheostomy/laryngectomy patients) or other nasopharyngeal or
oropharyngeal anomalies that do not allow for sampling using swabs.
B. Do not understand oral or written Danish
Valby COVID19 testcenter
Copenhagen, Denmark
Investigator: Tobias Gredal
Tobias Todsen, MD
+35453545
tobias.todsen@regionh.dk
Not Provided