The aim of the study is to test a treatment known as "Cognitive Muscular Therapy (CMT)"for reducing breathlessness and improving autonomic function in patients with long-COVID.
A key symptom of long-COVID is dysfunctional breathing, characterised by an alteration in
the muscular and mechanical control of breathing, such as altered movement/coordination
of diaphragm and ribs. Long-COVID patients also experience symptoms such as dizziness and
fatigue, which have been linked to dysautonomia (dysfunction of the nervous system
controlling automatic body functions). Importantly, dysautonomia is connected to
alterations in breathing mechanics. Specifically, rapid breathing, high in the chest, is
associated with increased activity in the fight-or-flight system and decreased activity
in the rest-and-repair system. Given this link, interventions capable of improving
breathing mechanics could alleviate many long-COVID symptoms. However, current breathing
retraining methods lack visualisation of breathing mechanics and do not integrate a
whole-body approach to improving postural control.
We have developed a clinical system which can visualise breathing mechanics in real-time,
providing patients with a "window into their body". We propose to integrate this system
within a new intervention, known as Cognitive Muscular Therapy (CMT). CMT integrates
psychological informed physiotherapy with training to reduce overactivation of postural
muscles which can interfere with the mechanics of breathing. We propose to test this
combined intervention on 20 people with Long-COVD to understand if we can improve
respiratory function and symptoms associated with dysautonomia. If successful, this pilot
study could pave the way for large-scale studies in long-COVID
Behavioral: Cognitive Muscular Therapy
Psychologically informed physiotherapy which integrates training to reduce overactivity
of postural muscles which can interfere with the mechanics of breathing.
Behavioral: Breathing visualisation
Breathing visualisation; Data from two 3D camera are combined and used to calculate
respiratory volumes. These volumes are then used to drive an animation of breathing so
that the patient can understand how their breathing pattern compares to an optimal
pattern. Note this is not a medical device as data from this system is only used for
education and not for diagnostic or treatment decisions.
Inclusion Criteria:
- Above 18 years old
- Experience moderate/severe breathlessness, quantified using the Modified COVID-19
Yorkshire Rehabilitation Scale (C19-YRSm) scale.
- Speak and understand English sufficiently to read the information sheet and sign the
consent form
- Ability to stand without any assistive device for at least 20 minutes (to ensure
sufficient capacity to complete the intervention)
Exclusion Criteria:
- Dementia or other major cognitive impairment
- BMI >32 (as increased subcutaneous fat prevents use of breathing measurement system)
- Current smoker or smoked regularly within last 6 months
- Any cardiorespiratory disease that requires medical intervention (except asthma
management)
- Currently receiving physiotherapy-based treatment for LC or breathing pattern
disorder
- Significant respiratory co-morbidity (e.g. COPD, uncontrolled Asthma)
University of Salford
Manchester, Greater Manchester, United Kingdom
Not Provided