Official Title
Cognitive Function Analysis and qEEG Study in Long COVID-19 Syndrome Patients
Brief Summary

Over than 30% individuals with COVID-19, including the asymptomatic ones, and around 80%of patients hospitalized with COVID-19 may experience post-COVID sequelae, which iscommonly referred to as Long COVID Syndrome. This condition has ties to decreasedcognitive function and may lead to neuropsychiatric disorders but still need to bestudied further. Using a cross-sectional design, this study will analyze the relationshipbetween cognitive function and neuropsychiatric disorders with brain wave activity inLong COVID patients.The investigators conducted assessments utilizing the quantitative electroencephalogram(qEEG) measurement method and interviews using instruments such as the MOCA questionnaireand Self Rating Questionnaire (SRQ). With this qEEG examination, the investigators hopedthat there will be an imbalance/abnormality of brain wave activity that arises related toimpaired cognitive function.

Detailed Description

This study is aimed to analyze the cognitive function and neuropsychiatry disorders with
brain wave activity using qEEG that occurs after COVID/Long Covid Syndrome.

The whole procedure will run for approximately 12 weeks based on the long COVID range.

The determinants of long COVID patients include: never been vaccinated, old age,
comorbid, female population, and hospitalized patients.

The total number of subjects with the post-COVID syndrome in the proportion test is 30
subjects.

The measuring instruments used to measure the decline in cognitive function are the MOCA
questionnaire and Self Rating Questionnaire (SRQ).

The target population is post-COVID-19 patients with Long COVID Syndrome.

The accessible population is post-COVID-19 patients who have been treated at RSCM Kiara
and have regular checkups at the RSCM polyclinic with Long COVID Syndrome for 12 weeks or
more.

The control population is post-COVID-19 patients who managed to recover without symptoms.

The Long COVID Syndrome patients who meet the inclusion criteria and have signed the
consent.

Recruiting
Long COVID-19 Syndrome

Device: Quantitative Electroencephalography

Each qEEG examination of one person lasted about 20 minutes and included two stages: the
first-recording of brain waves with eyes closed (5 min), the other with eyes open (5 min)

Eligibility Criteria

Inclusion Criteria:

1. Post-COVID-19 patients with Long COVID-19 Syndrome

2. Over 18 years old

3. Willing to participate in the research

4. Completed the Montreal Cognitive Assessment (MoCA) and Self Rating Questionnaire
(SRQ)

Exclusion Criteria:

1. Patients with neuropsychiatric disorders before being infected with COVID-19

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Indonesia
Locations

Rumah Sakit Cipto Manunkusumo
Jakarta Pusat, DKI Jakarta, Indonesia

Investigator: Yetty Ramli, MD
Contact: +62811163843
yettyramli@gmail.com

Investigator: Yetty Ramli, MD

Contacts

Yetty Ramli, MD
+62811163843
yettyramli@gmail.com

Dyah Tunjungsari, MD
+628119884224
penelitian.neuroui@gmail.com

Not Provided

Indonesia University
NCT Number
Keywords
Long COVID-19 syndrome
Covid-19
Quantitative electroencephalography
Case-control study
MeSH Terms
COVID-19
Post-Acute COVID-19 Syndrome
Syndrome