Official Title
Automated Oxygen Titration - Monitoring and Weaning in Patients With Infectious Pneumonia Requiring Oxygen - Impact on the Number of Interventions for Healthcare Workers. An Innovative Device to Manage Patients With COVID-19 Pneumonia COVID Study (Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decreaseduring Pneumonia)
Brief Summary

There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers. Among the WHO's primary strategic objectives for the response to COVID-19, the first was to limit human-to-human transmission, including reducing secondary infections among close contacts and health care workers. Automated oxygen titration, weaning and monitoring (FreeO2 device) may be a solution to reduce the number of interventions of healthcare workers related to oxygen therapy, to reduce complications related to oxygen and to improve monitoring.

Unknown status
Coronavirus
Pneumonia
Oxygen Toxicity

Other: Standard administration of oxygen flow

The investigator recommended SpO2 target of 90-94%. The investigator will recommend that low/high SpO2 alarms be set at 88% and 96% if continuous oximetry is used.
In this group the SpO2 was recorded any time with FreeO2 device - recording mode

Device: Automated oxygen administration - FreeO2

In this group, oxygen administration will be delivered with FreeO2 (automated oxygen titration) with SpO2 target set at 92% (to maintain oxygenation in the recommended SpO2 target: 90-94%)

Eligibility Criteria

Inclusion Criteria:

- Age> 18 years old

- patients with acute respiratory failure related to suspected community acquired
pneumonia (viral and non viral) requiring oxygen therapy < 6 L/min (or FiO2< 0.50) (to
maintain SpO2 between 90 and 94% SpO2) without criteria for immediate intubation or
ICU transfer.

- Patients hospital admission < 72 hours

Exclusion Criteria:

- shock state,

- no SpO2 signal available,

- patient agitation,

- pH < 7.30 (if blood gas available)

- PaCO2 > 50 mmHg, (if blood gas available) or chronic hypercapnia history

- Non invasive respiratory support (NIV, High flow Nasal Therapy (HFNT)) at study
inclusion

- Withdrawal of life support or palliation as the goal of care

- patients' or next of kin refusal to participate to the study

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Canada
Locations

Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
Quebec, Canada

Investigator: Pierre-Alexandre Bouchard
Contact: 418-656-8711
pierre-alexandre.bouchard@criucpq.ulaval.ca

Investigator: Francois Lellouche

Contacts

François Lellouche
418-656-8711 - 3572
francois.lellouche@criucpq.ulaval.ca

Pierre-Alexandre Bouchard
418-656-8711 - 2712
pierre-alexandre.bouchard@criucpq.ulaval.ca

Francois Lellouche, Principal Investigator
IUCPQ-UL

Laval University
NCT Number
MeSH Terms
Pneumonia