Official Title
Multi-Center Clinical Performance Evaluation of the NeuMoDx SARS-CoV-2 Assay on the NeuMoDx Molecular Systems
Brief Summary

A multicenter study, using prospectively collected, fresh (Category I) and frozen(Category II), residual/leftover nasopharyngeal (NP) swab in UTM/UVT specimens obtainedfrom symptomatic individuals suspected of COVID-19 infection. This study will evaluatethe NeuMoDx SARS-CoV-2 Assay's clinical performance on the NeuMoDx 288 and NeuMoDx 96Molecular Systems.

Detailed Description

Not Provided

Terminated
SARS-CoV-2 Acute Respiratory Disease

Diagnostic Test: NeuMoDx SARS-CoV-2 Assay

The NeuMoDx™ SARS-CoV-2 Assay is an automated, in vitro nucleic acid amplification test
intended for the qualitative detection of SARS-CoV-2 RNA in nasopharyngeal (NP) swabs in
transport medium obtained from symptomatic individuals suspected of COVID-19 infection.
The NeuMoDx SARS-CoV-2 Assay as performed on the NeuMoDx™ 288 Molecular System and
NeuMoDx™ 96 Molecular System incorporates automated RNA extraction to isolate target
nucleic acids from the specimen and real-time reverse transcription PCR targeting two
conserved regions of the SARS-CoV-2 genome.

Eligibility Criteria

Inclusion Criteria:

1. Any de-identified NP swab specimen in transport medium from a symptomatic individual
suspected of COVID-19 at the time of collection.

2. NP swab specimens obtained using a flexible mini-tip flocked swab and collected into
3mL Copan UTM [Cat. No. 305C] or BD UVT [Cat. No. 220531].

3. Prospective specimens, fresh (Category I) shall be tested within:

1. (4) hours when held at room temperature, or

2. (3) days when held at (2 to 8°C), with cold storage starting within (4) hours
of collection.

4. Minimum volume of ≥ 2mL.

Exclusion Criteria:

1. Required information unable to be obtained from the associated medical chart.

2. Specimens that remained on-board the NeuMoDx System for > (8) hours prior to
processing.

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A
Countries
United Kingdom
Locations

QIAGEN Gaithersburg, Inc
Manchester, United Kingdom

Not Provided

QIAGEN Gaithersburg, Inc
NCT Number
MeSH Terms
Respiratory Tract Diseases
Respiration Disorders