Official Title
ReportAge-COVID Project: Clinical and Biological Predictors of COVID-19 Disease in Older Patients
Brief Summary

The project is an observational, prospective study. Its aim is to deepen our understanding of COVID-19 in older patients hospitalized and diagnosed with COVID-19. In particular, socioeconomic, diagnostic, biological, functional, therapy data will be collected at the patients' admission, during hospital stay, at the discharge and 1, 3, 6, 12 months after discharge. Results and findings will help support changes in clinical practice and decision making, with the aim to reduce the use of healthcare services and the healthcare expenditure.

Detailed Description

Current knowledge about clinical and biological characteristics of COVID 19 among older
people is very limited. A better comprehension of the clinical picture of older patients
affected by COVID-19, (e.g. frailty, multimorbidity and polypharmacy patterns and functional
performance) may significantly contribute to deepen our understanding of the clinical
epidemiology knowledge of COVID-19 among hospitalized older people.

Therefore, the ReportAge-COVID project aims to collect - using a minimum clinical and
biological data set - a series of data and indicators on the conditions of elderly patients
that are suspected of having a compatible clinical picture or were confirmed positive for
COVID-19. Data will be collected at the patients' admission, during hospital stay, at
discharge and 1, 3, 6, 12 months after discharge.

In particular, the following specific pieces of information will be gathered:

- routinely collected demographic, socioeconomic, clinical, biological and diagnostic data

- frailty condition (by using the clinical frailty scale)

- assessment of the functional capacities through ADL and IADL tests

- health conditions; nutritional status; medications; treatments and procedures

- biomarkers of aging including cytokines and anti-inflammatory molecules, previously
identified in a focus group of experts

Results and findings will help support changes in clinical practice and decision making, with
the aim of reducing adverse outcomes, the worsening of health conditions in the elderly
population, the use of healthcare services and, as a consequence, lower healthcare
expenditure.

Recruiting
COVID-19
Eligibility Criteria

Inclusion Criteria:

- diagnosis of COVID-19

Exclusion Criteria:

- no informed consent

Eligibility Gender
All
Eligibility Age
Minimum: 65 Years ~ Maximum: N/A
Countries
Italy
Locations

IRCCS INRCA Hospital
Ancona, Italy

IRCCS INRCA Hospital
Casatenovo, Italy

IRCCS INRCA Hospital
Fermo, Italy

Contacts

Anna Rita Bonfigli, PhD
00390718003719
a.bonfigli@inrca.it

Istituto Nazionale di Ricovero e Cura per Anziani
NCT Number
Keywords
Covid-19
older people
SARS-CoV-2
frailty
physical function
biomarkers of inflammation
MeSH Terms
COVID-19