Justification: among the sequelae of Covid-19 in clinical practice we frequently findpersistent neuromusculoskeletal pain. Prevalence data and the underlying mechanisms ofsuch pain are very limited in the scientific literature. Therefore, with this research wewill try to answer these questions.Main objective: to determine and characterize persistent musculoskeletal pain in Covid-19patients.Method: two phases. First, a descriptive cross-sectional study will be carried out toestimate the prevalence of Long Covid Pain (LCP). Second phase, a case-control study willbe carried out using the sample obtained in the first phase as the population. The samplewill be divided into two groups: post-Covid-19 patients with LCP and post-Covid-19patients without persistent pain (control group). The two groups will be matchedaccording to sex, age and level of severity of the pathology.An assessment and comparison between groups will be made of the following variables:central sensitization, healthy physical condition and blood test values, which will beevaluated by means of physical examination, questionnaires and laboratory tests.Applicability of the results: this is a pioneering project at the national level, whichwould determine more reliably the prevalence of LCP in postcovid and could be a firststep in the search for the best therapeutic strategies for these patients. This wouldhelp to improve the quality of life of these patients and to better manage the social andhealthcare resources used in their treatment.