This research study is being done to find out what the longer-term physiologicalconsequences of COVID-19 are, and to determine if exercise therapy can help improve lungfunction, heart function and overall fitness, and reduce symptoms in people recoveringfrom SARS-CoV-2.
The purpose of this research is to see if taking part in structured exercise training
will improve the ability to exercise, the function of the lungs and the function of the
heart, and reduce symptoms of fatigue and breathlessness in people recovering from
COVID-19. After enrollment all patients will complete exercise testing, lung function
testing, and cardiac imaging. Patients will be randomized to either 8 weeks of exercise
training (4-5 times per week) or will continue standard medical care. All patients will
undergo detailed exercise testing, lung function testing, and cardiac imaging after the
intervention.
Other: Exercise Training
8 week home-based exercise therapy 4-5 times/week
Inclusion Criteria:
- Aged 21 to 75 years.
- History of RT-PCR proven SARS-CoV-2 infection.
- Deemed 'recovered' from SARS-CoV-2 infection.
- Not clinically obese (BMI ≥ 36) and/or suffer from musculoskeletal or other
conditions that would limit exercise participation.
- No evidence of cardiac ischemia at rest or during exertion (via ECG).
- Able to provide written informed consent.
Exclusion Criteria:
- Individuals less than 21 or more than 75 years old.
- Not able to take part in structured exercise training due to injury or other
conditions that would put person at risk during exercise.
- Unable to provide written informed consent.
Mayo Clinic in Florida
Jacksonville, Florida, United States
Investigator: Chary Aleger
Contact: 904-953-4603
Aleger.chary@mayo.edu
Bryan Taylor, PhD, Principal Investigator
Mayo Clinic