Official Title
Altered Respiratory Compliance Under Invasive Mechanical Ventilation in SARS-CoV-2 & Development of Respiratory Sequels
Brief Summary

The goal is to study the association between the value of the compliance of therespiratory system at the first day of the initiation of invasive mechanical ventilationand the presence of respiratory sequelae at a distance from the COVID-19 infection withthe hypothesis that patients who have presented an alteration of the compliance of therespiratory system are at greater risk of developing respiratory sequelae.Studying the altered compliance of the respiratory system in ARDS secondary to COVID-19and its relationship to the development of respiratory sequelae would help us to improvethe management of patients with COVID-19.

Detailed Description

Not Provided

Unknown status
ARDS Due to Disease Caused by SARS Co-V-2
Respiratory Compliance
Sequels of COVID
Eligibility Criteria

Inclusion Criteria:

- Hospitalized in intensive care medicine between 01/03/2030 and 01/09/2022 (with
invasive mechanical ventilation for at least 48 hours for a SARS-CoV-2 infection
documented by RT-PCR) who were followed in pulmonary outpatient medicine at least 3
months after their hospitalization in intensive care medicine and before 01/12/2022
and who had respiratory sequelae during this period.

- Hospitalized in intensive care medicine between 01/03/2020 and 01/12/2021 (with
invasive mechanical ventilation for at least 48 hours for SARS-CoV-2 infection
documented by RT-PCR) who were followed up in pulmonary outpatient medicine but did
not have respiratory sequelae between 01/06/2020 and 01/12/2022.

Exclusion Criteria:

- Documented underlying respiratory pathology.

- Pneumothorax within the first 10 days.

- Patient requiring extracorporeal circulatory support.

- Refusal to participate

- Persons referred to in articles L. 1121-5, L. 1121-7 and L1121-8 of the public
health code: Pregnant woman, parturient or breastfeeding mother / Minor (not
emancipated) / Adult subject to a legal protection measure (guardianship,
curatorship, safeguard of justice) / Adult unable to express his consent

- Persons deprived of liberty by a judicial or administrative decision, persons under
psychiatric care under articles L. 3212-1 and L. 3213-1.

- Respiratory system compliance data not available on the computer software

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
France
Locations

Valentin Simon
Nancy, France

Investigator: valentin simon
Contact: 0686435505
simon1.valentin1@gmail.com

Contacts

simon valentin, MD
+3383153405
simon.valentin@live.fr

Not Provided

Central Hospital, Nancy, France
NCT Number