Official Title
Acute Liver Injury in Patients With Pneumonia and Its Impact on Hospital Stay and Outcome
Brief Summary

Acute liver injury (ALI) is defined as an acute derangement in liver function testsassociated with liver-related coagulopathy, in the absence of underlying chronic liverdisease.A subset progress to acute liver failure ,Acute liver failure represent a more severeliver injury results in hepatic encephalopathy

Detailed Description

Acute liver injury is associated with a spectrum of haemostatic changes, including
thrombocytopenia and reduced platelet function, reduced plasma levels of many coagulation
factors such as factor (F)VII and increased levels of FVIII .

Pneumonia is an acute inflammation of the lower respiratory tract. Lower respiratory
tract infection is a major cause of mortality worldwide .Pneumonia is most common at the
extremes of life.

In adults, pneumonia can be broadly classified, on the basis of chest radiographic
appearance, into lobar pneumonia, bronchopneumonia and pneumonia producing an
interstitial pattern.

There is lack of data regarding outcome and hospital stay in patients with pneumonia who
develop acute liver injury.

Not yet recruiting
Acute Liver Injury
Pneumonia

Other: Acute Liver Injury

To evaluate the impact of acute liver injury in patients with pneumonia on hospital stay
and outcome.

Eligibility Criteria

Inclusion Criteria:

1. Patients with pneumonia that developed Acute Liver Injury

2. Covid 19 pneumonia

3. Patients With acute liver injury only.

Exclusion Criteria:

1. Cancer

2. Immunocompromised patients i.e HIV patients and patients who take immunosuppressive
medications.

3. Patients who younger than 18 yrs old

4. pregnancy

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 68 Years
Countries
Egypt
Locations

Faculty Of Medicine
Asyut 359783, Egypt

Contacts

Beshoy Yousef, MSc
01114761284
Beshoyyoussef18@gmail.com

Zain Elabdeen Ahmed, Professor
01115596820
drzain73@yahoo.com

Zain Elabdeen Ahmed, Professor, Study Chair
Assuit Faculty of Medicine

Assiut University
NCT Number
Keywords
Acute Liver Injury
Pneumonia
COVID19
MeSH Terms
Pneumonia
COVID-19