Official Title
Acceptance and Commitment Therapy- Based Group Therapy for Mental Health in Neurological Disorders
Brief Summary

The goal of this clinical trial is to examine the efficacy of this manual for mentalhealth in people with mixed neurological disorders, including post-COVID. Theseconditions are often associated with cognitive impairment, which may hamper the effectsof psychoterapy. Executive functioning and especially the ability to abstract thinkingmay be useful for individuals using Acceptance and Commitment Therapy. Therefore, themain questions research questions are: - Is this intervention effective in improving mental health? - Do executive functions predict the extent of social participation and mental health at the end of therapy? Participants will take part in 8 weekly group therapy sessions of 100 minutes each.

Detailed Description

Mental health issues, especially depression, anxiety, and stress, are common in people
with neurological disorders and post-COVID but often neglected and hence, remain
untreated. Acceptance and Commitment Therapy (ACT) is a promising approach to assist
people in adapting to their conditions by improving "psychological flexibility".

A previous study translated an adapted group psychotherapy manual for stroke survivors
into German and demonstrated its feasibility. This pilot study also gave first
indications on the manual's efficacy in reducing symptoms of anxiety, depression, and
stress. The aim of this study is to investigate the efficacy of this ACT-based group
therapy. People with neurological disorders may have impairments in executive functions,
which can affect the psychotherapeutic process. Since ACT often uses metaphors and
imagery, executive functions, particularly the ability to abstract, could influence the
efficacy of the therapy and are therefore being investigated in this study. The program
includes 8 weekly sessions with a session length of 100 minutes.

Recruiting
Neurological Disorders
Mental Health
Executive Function (Cognition)
Depression/Anxiety
Stress
Brain Injury
Post-COVID

Behavioral: ACT-based group therapy

ACT-based group therapy based on the manual "Living Well with Neurological Conditions"
published by Hill et al. (2017; NHS Fundation Trust; available: https://goo.gl/aX6qB5).
The manual was translated into German and adapted by shortening sessions, simplifying
language and adapting exercises based on clinical experience. The publication of the
feasibility study for the adapted manual is currently in preparation. The group therapy
includes eight weekly sessions with a duration of 100 minutes each. Three to six
individuals participate in a group. The therapy is delivered by at least one licensed
psychotherapists. A co-therapist might be included based on individual needs of the group
members.

Eligibility Criteria

Inclusion Criteria:

- Value above a cut-off of the DASS-21 subscales (depression > 10, anxiety > 6, and
stress > 10)

- Sufficient cognition and language ability (clinical rating)

- Sufficient therapy motivation (clinical rating)

Exclusion Criteria:

- Behavioral disorders (e.g., high irritability or apathy in clinical rating)

- Other severe mental disorder (dementia, psychosis, personality disorders,
intellectual disability)

- Simultaneous psychotherapy or neuropsychological therapy

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Germany
Locations

Neuropsychologische Hochschulambulanz Bielefeld
Bielefeld, Germany

Investigator: Simon Ladwig, PhD
Contact: +49 (0) 521 106 67533
simon.ladwig@uni-bielefeld.de

Contacts

Simon Ladwig, PhD
+49 (0) 521 106 67533
simon.ladwig@uni-bielefeld.de

Franziska Supe, M.Sc.
+49 (0) 521 106 67533
franziska-marie.supe@uni-bielefeld.de

Katja Werheid, Prof, Study Chair
Bielefeld University

Bielefeld University
NCT Number
Keywords
Acceptance and Commitment Therapy (ACT)
Group therapy
neurological disorders
Brain Injury
Anxiety
Stress
depression
executive functioning
abstraction ability
Post-COVID
MeSH Terms
Brain Injuries
Nervous System Diseases
Depression