Official Title
Awake Prone Position in Hypoxemic Patients With Coronavirus Disease 19 (COVI-PRONE): A Randomized Clinical Trial
Brief Summary

The aim of the COVI-PRONE Trial is to determine if early awake prone positioning in COVID-19 patients with hypoxemic respiratory failure; irrespective of the mode of oxygen delivery; reduces the need for invasive mechanical ventilation.

Recruiting
Corona Virus Infection
COVID19

Procedure: Awake Proning
The duration of proning will be a total of 8-10 hours with 1-2 hours break in supine position.
Intervention - Awake Proning

Eligibility Criteria

Inclusion Criteria:

Adults ≥ 18 years of age. Suspected or confirmed COVID-19. Defined as: a positive PCR for
SARS CoV-2 or pending PCR results for patients that are suspected to have COVID-19.

Hypoxemia on room air (SPO2

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years
Countries
Canada
Saudi Arabia
Contacts

Sarah Culgin
905-522-1155 32873
sculgin@stjoes.ca

Zainab Al Duhalib
zainajd@gmail.com

Waleed Alhazzani
Principal Investigator
St. Joseph's Healthcare Hamilton

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Yaseen Arabi
Principal Investigator
King Saud Bin Abdulaziz University for Health Sciences

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Zainab Alduhailib
Principal Investigator
King Faisal Specialist Hospital and Research Center, Jeddah

St. Joseph's Healthcare Hamilton
King Abdullah International Medical Research Center (KAIMRC)
McMaster University
Canadian Institutes of Health Research (CIHR)
NCT Number
MeSH Terms
Coronavirus Infections
Severe Acute Respiratory Syndrome